{ "_id": "6a1beadf1d7bb097a0a1ee57", "Package": "phase12designs", "Type": "Package", "Title": "Comprehensive Tools for Running Model-Assisted Phase I/II Trial\nSimulations", "Version": "0.3.1", "Authors@R": "c(person(given = \"Angela\", family = \"Cao\", role = c(\"aut\", \"cre\"), email = \"cao.t.angela@gmail.com\"),\nperson(given = \"Haolun\", family = \"Shi\", role = \"ctb\"))", "Author": "Angela Cao [aut, cre], Haolun Shi [ctb]", "Maintainer": "Angela Cao ", "Description": "Provides a comprehensive set of tools to simulate,\nevaluate, and compare model-assisted designs for early-phase\n(Phase I/II) clinical trials, including: - BOIN12 (Bayesian\noptimal interval phase 1/11 trial design; Lin et al. (2020)\n), - BOIN-ET (Takeda, K., Taguri, M.,\n& Morita, S. (2018) ), - EffTox (Thall,\nP. F., & Cook, J. D. (2004)\n), - Ji3+3 (Joint i3+3\ndesign; Lin, X., & Ji, Y. (2020)\n), - PRINTE (probability\nintervals of toxicity and efficacy design; Lin, X., & Ji, Y.\n(2021) ), - STEIN (simple\ntoxicity and efficacy interval design; Lin, R., & Yin, G.\n(2017) ), - TEPI (toxicity and efficacy\nprobability interval design; Li, D. H., Whitmore, J. B., Guo,\nW., & Ji, Y. (2017) ), -\nuTPI (utility-based toxicity Probability interval design; Shi,\nH., Lin, R., & Lin, X. (2024) ). Includes\nflexible simulation parameters that allow researchers to\nefficiently compute operating characteristics under various\nfixed and random trial scenarios and export the results.", "License": "MIT + file LICENSE", "Encoding": "UTF-8", "VignetteBuilder": "knitr", "RoxygenNote": "7.3.2.9000", "NeedsCompilation": "no", "Packaged": { "Date": "2026-05-31 07:20:04 UTC", "User": "root" }, "Config/pak/sysreqs": "make libicu-dev", "Repository": "https://angela-cao.r-universe.dev", "Date/Publication": "2025-09-02 06:30:02 UTC", "RemoteUrl": "https://github.com/cran/phase12designs", "RemoteRef": "HEAD", "RemoteSha": "5a5f52455362b9a5ab63c728922aea43660d39f8", "MD5sum": "5bf955d96bccd8442d7918c08b4206da", "_user": "angela-cao", "_type": "src", "_file": "phase12designs_0.3.1.tar.gz", "_fileid": "535b5dba5e2fde467d550331883e3077c2d2c795d2968fdad00ba2c27ac5e8bf", "_filesize": 167984, "_sha256": "535b5dba5e2fde467d550331883e3077c2d2c795d2968fdad00ba2c27ac5e8bf", "_created": 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